![]() fast transformation through uracil to, at least, one more polar radioactive fraction. ![]() The same way of metabolism was found in UMF and UTF, i.e. Then radioactivity was quickly removed with the corresponding elimination half-life of 1.2 and 5.0 hours. Then radioactivity was quickly removed with the corresponding elimination half-life 1.0 and 3.8 hours.Īfter use 14S-UTF a dose of 4.86 mg/kg, the Cmax value, the making 1.291 mg/kg, were reached in 20 minutes. Then radioactivity was quickly removed with elimination half-life 0.5 and 0.6 hours for alpha distribution and beta elimination, respectively.Īfter use 14S-TsMF a dose of 4.83 mg/kg, the Cmax value, the making 1.567 mg/kg, were reached in 20 minutes. The purposes of this research consisted in assessment of absorption and pharmacokinetics of UMF, CMF and also UTF.Īfter use 14S-UMF a dose of 4.97 mg/kg, the maximum concentration in plasma (Cmax) making 1.749 mg/kg were reached in 10 minutes. Pharmacokinetics Components properties of this drug have organic origin which are already present at biological liquids, causes difficulty of carrying out pharmacokinetic researches of drug, and it formed the basis of carrying out a research with use of a product, marked radioactive isotopes. The Code of automatic telephone exchange N07XX Contents of capsules powder of white color, is hygroscopic.ĭrugs for treatment of diseases of nervous system other 2, body of gray color, lid of blue color. Structure of the capsule: ferrous oxide black E172, titan E171 dioxide, gelatin, E132 indigo carmine. Of the Structure One Capsule Capsule containsĪctive agents: cytidine 5 dinatrium monophosphate 5.00, uridine 5 trisodium triphosphate, uridine 5 dinatrium diphosphate, uridine 5 dinatrium monophosphate (only) 3.00 (it is equivalent to uridine content) (1.33).Įxcipients: citric acid, citrate sodium dihydrate, magnesium stearate, silicon dioxide colloidal, Mannitolum.
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